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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9309538 B1

PDFFull Text
Date of Patent:
Apr. 12, 2016

Filed:

Sep. 10, 2009

Beta-glucosidase variants having improved activity, and uses thereof

Applicants:

Nicolas Lopes-ferreira, Croisilles, FR;

Antoine Margeot, Paris, FR;

Hugues Mathis, Bussy Saint Georges, FR;

Laurent Fourage, Calvisson, FR;

Inventors:

Nicolas Lopes-Ferreira, Croisilles, FR;

Antoine Margeot, Paris, FR;

Hugues Mathis, Bussy Saint Georges, FR;

Laurent Fourage, Calvisson, FR;

Assignees:

IFP Energies Nouvelles, Rueil Malmaison, FR;

PROTEUS, Nimes, FR;

Attorney:

McDonnell Boehnen Hulbert & Berhgoff

Primary Examiner:

Iqbal H Chowdhury

Int. Cl.
CPC ...
C12Q 1/34 (2006.01); C12P 19/02 (2006.01); C12P 1/00 (2006.01); C12N 9/24 (2006.01); C12N 1/20 (2006.01); C12N 1/00 (2006.01); C12N 15/00 (2006.01); C12P 7/06 (2006.01); C07H 21/04 (2006.01); C12P 7/04 (2006.01); C12P 7/10 (2006.01); C12P 7/16 (2006.01); C12P 19/14 (2006.01); C12N 9/42 (2006.01);
U.S. Cl.
CPC ...
C12P 7/04 (2013.01); C12N 9/2445 (2013.01); C12P 7/10 (2013.01); C12P 7/16 (2013.01); C12P 19/02 (2013.01); C12P 19/14 (2013.01); C12Y 302/01021 (2013.01); Y02E 50/10 (2013.01); Y02E 50/16 (2013.01); Y02P 20/52 (2015.11);
Abstract

The present invention relates to the expression and optimization of enzymes involved in lignocellulosic biomass decomposition. The present invention relates more particularly to beta-glucosidase variants comprising at least one modification among the amino acids located at positions 225, 238, 240 and 241, according to the numbering in SEQ ID No. 2 ofbeta-glucosidase, and also relates to the use of said variants having improved effectiveness in methods for cellulose decomposition and biofuel production.

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