The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2016
Filed:
Mar. 04, 2014
Jeremy Baryza, Cambridge, MA (US);
Keith Bowman, Cambridge, MA (US);
Andrew Geall, Cambridge, MA (US);
Tanzina Labonte, Cambridge, MA (US);
Cameron Lee, Cambridge, MA (US);
Chandra Vargeese, Cambridge, MA (US);
Laura West, Cambridge, MA (US);
Junping Zhao, Cambridge, MA (US);
Jeremy Baryza, Cambridge, MA (US);
Keith Bowman, Cambridge, MA (US);
Andrew Geall, Cambridge, MA (US);
Tanzina Labonte, Cambridge, MA (US);
Cameron Lee, Cambridge, MA (US);
Chandra Vargeese, Cambridge, MA (US);
Laura West, Cambridge, MA (US);
Junping Zhao, Cambridge, MA (US);
NOVARTIS AG, Basel, CH;
Abstract
Disclosed are formulation and optimization protocols for delivery of therapeutically effective amounts of biologically active agents to liver, tumors, and/or other cells or tissues. Also provided are compositions and uses for cationic lipid compounds of formula (I). The invention also relates to compositions and uses for stealth lipids of formula (XI). Also provided are processes for making such compounds, compositions, and formulations, plus methods and uses of such compounds, compositions, and formulations to deliver biologically active agents to cells and/or tissues.