The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2016
Filed:
Feb. 12, 2014
Applicants:
Janine R. Shulok, Newton, MA (US);
Feng Cong, Quincy, MA (US);
Mark C. Fishman, Newton Center, MA (US);
Seth Ettenberg, Melrose, MA (US);
Michael Bardroff, Munich, DE;
Mariel Donzeau, Strasbourg, FR;
Stefanie Urlinger, Nürnberg, DE;
Inventors:
Janine R. Shulok, Newton, MA (US);
Feng Cong, Quincy, MA (US);
Mark C. Fishman, Newton Center, MA (US);
Seth Ettenberg, Melrose, MA (US);
Michael Bardroff, Munich, DE;
Mariel Donzeau, Strasbourg, FR;
Stefanie Urlinger, Nürnberg, DE;
Assignee:
NOVARTIS AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/22 (2006.01); C07K 16/18 (2006.01); A61K 31/675 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 31/675 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/18 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/92 (2013.01);
Abstract
Antibodies and fragments that bind to the protein target Dickkopf (DKK1) are provided, as are methods of use and kits, for treating a target cell, in particular, a cell associated with an osteolytic condition.