The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2016

Filed:

Aug. 31, 2012
Applicants:

James J. Cali, Verona, WI (US);

Sarah Duellman, Fitchburg, WI (US);

Dieter Klaubert, Arroyo Grande, CA (US);

Donna Leippe, Middleton, WI (US);

Martha O'brien, Madison, WI (US);

John Shultz, Verona, WI (US);

Jolanta Vidugiriene, Fitchburg, WI (US);

Wenhui Zhou, Santa Maria, CA (US);

Mary Sobol, McFarland, WI (US);

Inventors:

James J. Cali, Verona, WI (US);

Sarah Duellman, Fitchburg, WI (US);

Dieter Klaubert, Arroyo Grande, CA (US);

Donna Leippe, Middleton, WI (US);

Martha O'Brien, Madison, WI (US);

John Shultz, Verona, WI (US);

Jolanta Vidugiriene, Fitchburg, WI (US);

Wenhui Zhou, Santa Maria, CA (US);

Mary Sobol, McFarland, WI (US);

Assignee:

PROMEGA CORPORATION, Madison, WI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/04 (2006.01); C07D 277/68 (2006.01); C07D 487/04 (2006.01); C12Q 1/32 (2006.01); C07D 493/10 (2006.01); C12Q 1/66 (2006.01); C07D 497/10 (2006.01); C07F 9/6558 (2006.01); C07F 9/6561 (2006.01); G01N 21/76 (2006.01); G01N 33/50 (2006.01); G01N 33/573 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/32 (2013.01); C07D 277/68 (2013.01); C07D 417/04 (2013.01); C07D 487/04 (2013.01); C07D 493/10 (2013.01); C07D 497/10 (2013.01); C07F 9/6561 (2013.01); C07F 9/65583 (2013.01); C12Q 1/66 (2013.01); G01N 21/763 (2013.01); G01N 33/5038 (2013.01); G01N 33/5735 (2013.01); G01N 33/582 (2013.01);
Abstract

The present invention provides compounds and methods for assaying redox state of metabolically active cells and methods for assaying enzyme activity and/or metabolite level by coupling to redox defining co-factor NAD(P)/NAD(P)H measurement.


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