The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
Mar. 18, 2014
Applicant:
Danisco Us Inc., Palo Alto, CA (US);
Inventor:
Huaming Wang, Fremont, CA (US);
Assignee:
Danisco US Inc., Palo Alto, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); C12N 1/14 (2006.01); C12N 9/02 (2006.01); C12N 9/48 (2006.01); C12N 9/62 (2006.01); C12N 9/88 (2006.01); C12N 15/52 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C12N 1/14 (2013.01); C12N 9/0061 (2013.01); C12N 9/48 (2013.01); C12N 9/62 (2013.01); C12N 9/88 (2013.01); C12N 15/52 (2013.01); C12P 21/00 (2013.01); C12P 21/02 (2013.01); C12Y 110/03002 (2013.01);
Abstract
A recombinant filamentous fungal cell (e.g.) having one or more inactivated chromosomal genes is provided. The chromosomal genes in some embodiments correspond to derA, derB, htmA, mnn9, mnn10, ochA, dpp4, dpp5, pepAa, pepAb, pepAc, pepAd, pepF and combinations thereof. The recombinant fungal cells may include further inactivated chromosomal genes which correspond to pepA, pepB, pepC and pepD. The recombinant filamentous fungal cells may include a heterologous nucleic acid encoding a protein of interest. Also provided are methods of producing a protein of interest in said recombinant filamentous fungal cell.