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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9267148 B1

PDFFull Text
Date of Patent:
Feb. 23, 2016

Filed:

Oct. 29, 2010

Methods for the biosynthesis of taurine or hypotaurine in cells

Applicants:

Frank J. Turano, Baltimore, MD (US);

Kathleen A. Turano, Baltimore, MD (US);

Peter S. Carlson, Baltimore, MD (US);

Alan M. Kinnersley, Baltimore, MD (US);

Inventors:

Frank J. Turano, Baltimore, MD (US);

Kathleen A. Turano, Baltimore, MD (US);

Peter S. Carlson, Baltimore, MD (US);

Alan M. Kinnersley, Baltimore, MD (US);

Assignee:

PLANT SENSORY SYSTEMS, LLC, Baltimore, MD (US);

Attorney:

Rothwell, Figg, Ernst & Manbeck P.C.

Primary Examiner:

Russell Kallis

Int. Cl.
CPC ...
C12N 15/82 (2006.01); A61K 31/185 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8243 (2013.01); A61K 31/185 (2013.01); C12N 15/8253 (2013.01); C12N 15/8261 (2013.01); C12N 15/8271 (2013.01); C12N 15/8273 (2013.01); C12N 15/8279 (2013.01);
Abstract

The present invention describes an approach to increase taurine or hypotaurine production in prokaryotes or eukaryotes. More particularly, the invention relates to genetic transformation of organisms with genes that encode proteins that catalyze the conversion of cysteine to taurine, methionine to taurine, cysteamine to taurine, or alanine to taurine. The invention describes methods for the use of polynucleotides that encode functional cysteine dioxygenase (CDO), cysteine dioxygenase (CDO) and sulfinoalanine decarboxylase (SAD) or glutamate decarboxylase (GAD), cysteamine dioxygenase (ADO), taurine-pyruvate aminotransferase (TPAT), TPAT and sulfoacetaldehyde acetyltransferase (SA), taurine dioxygenase (TDO) or the small (ssTDeHase) and large subunits of taurine dehydrogenase (lsTDeHase) polypeptides in plants to increase taurine, hypotaurine or taurine precursor production. The preferred embodiment of the invention is in plants but other organisms may be used. Increased taurine production in plants will enhance plant growth and development, yield, or tolerance to biotic and/or abiotic stresses and could be used as nutraceutical, pharmaceutical, or therapeutic compounds or as a supplement in animal feed.

Find Patent Forward Citations

Turano, Frank. (2016). Methods for the biosynthesis of taurine or hypotaurine in cells (U.S. Patent No. 9267148). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9267148

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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