The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2016

Filed:

Feb. 17, 2012
Applicants:

Xiangtian Long, Guangzhou, CN;

Danmei Dai, Chongqin, CN;

Andreas Brunner, Brig, CH;

Derek Kevin Watt, Lower Hutt, NZ;

Keith Clinch, Lower Hutt, NZ;

Sylvia Myrna Baars, Hamilton, NZ;

Rachel Anne Dixon, Wellington, NZ;

Gillian Mary Little, Essex, GB;

Cyrille Abel Sébastien Landreau, Essex, GB;

Nicolas Georges Rene Proisy, Hertfordshire, GB;

Inventors:

Xiangtian Long, Guangzhou, CN;

Danmei Dai, Chongqin, CN;

Andreas Brunner, Brig, CH;

Derek Kevin Watt, Lower Hutt, NZ;

Keith Clinch, Lower Hutt, NZ;

Sylvia Myrna Baars, Hamilton, NZ;

Rachel Anne Dixon, Wellington, NZ;

Gillian Mary Little, Essex, GB;

Cyrille Abel Sébastien Landreau, Essex, GB;

Nicolas Georges Rene Proisy, Hertfordshire, GB;

Assignee:

Alexion Pharmaceuticals, Inc., Cheshire, CT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 491/22 (2006.01); C07F 9/6574 (2006.01); C07D 491/14 (2006.01); C07D 491/147 (2006.01);
U.S. Cl.
CPC ...
C07F 9/65744 (2013.01); C07D 491/14 (2013.01); C07D 491/147 (2013.01);
Abstract

Provided herein are synthetic methods for preparing a compound of formula (I): Also provided herein are synthetic methods for preparing a compound of formula (XIII): The disclosure also provides useful intermediates, derivatives, prodrugs, and pharmaceutically acceptable salts, solvates and hydrates of the formula (I) and formula (XIII) compounds. These compounds are useful for treating diseases associated with molybdenum cofactor deficiency.


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