The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
Dec. 11, 2013
Applicant:
One Lambda, Canoga Park, CA (US);
Inventors:
Assignee:
ONE LAMBDA, Canoga Park, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 33/68 (2006.01); G01N 33/50 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6854 (2013.01); C07K 16/2833 (2013.01); G01N 33/505 (2013.01); G01N 33/543 (2013.01); G01N 2800/245 (2013.01); Y10T 436/25125 (2015.01);
Abstract
The invention is directed to methods of screening for HLA antibodies comprising detecting antibodies specific for native HLA antigens and denatured HLA antigens. The invention also provides for methods of removing antibodies specific for denatured HLA antigens or antibodies specific for native HLA antigens from a serum sample. In addition, the invention also provides for method of predicting whether a transplant recipient has an increased risk for rejecting the transplanted organ.