The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2016
Filed:
Oct. 25, 2011
John A. Mccauley, Maple Glen, PA (US);
Hemaka A. Rajapakse, Wyncote, PA (US);
Thomas J. Greshock, Collegeville, PA (US);
John Sanders, Philadelphia, PA (US);
Boyoung Kim, Lansdale, PA (US);
Vanessa L. Rada, Hatfield, PA (US);
Jonathan T. Kern, Souderton, PA (US);
Heather H. Stevenson, Ardmore, PA (US);
Mark T. Bilodeau, Lansdale, PA (US);
John A. McCauley, Maple Glen, PA (US);
Hemaka A. Rajapakse, Wyncote, PA (US);
Thomas J. Greshock, Collegeville, PA (US);
John Sanders, Philadelphia, PA (US);
Boyoung Kim, Lansdale, PA (US);
Vanessa L. Rada, Hatfield, PA (US);
Jonathan T. Kern, Souderton, PA (US);
Heather H. Stevenson, Ardmore, PA (US);
Mark T. Bilodeau, Lansdale, PA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
Disclosed are compounds of Formula (I): and the pharmaceutically acceptable salts thereof, wherein 'A' is S—; —SO—, —SO—, —O— or NR—, wherein Rac is H, or Calkyl and Rthrough Rare defined herein. Also disclosed are pharmaceutical formulations comprising a compound of Formula I and methods of treating, managing, or ameliorating diseases amenable to treatment, management, or amelioration by inhibition of LRRK2 kinase activity, for example, Parkinson's disease.