The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2015
Filed:
Mar. 09, 2015
Amphivena Therapeutics, Inc., San Francisco, CA (US);
Kristina Ellwanger, Heidelberg, DE;
Luke Evnin, San Francisco, CA (US);
Judith A. Fox, San Francisco, CA (US);
Ivica Fucek, Frankfurt, DE;
Jeanmarie Guenot, San Francisco, CA (US);
Stefan Knackmuss, Plankstadt, DE;
Lori Kunkel, San Francisco, CA (US);
Melvyn Little, St. Peter-Ording, DE;
Vera Molkenthin, Tannesberg, DE;
Erich Rajkovic, Schriesheim, DE;
Uwe Reusch, Maikammer, DE;
Claudia Wall, Bruehl, DE;
Michael Weichel, Bischofsheim, DE;
Eugene Zhukovsky, Mannheim, DE;
AMPHIVENA THERAPEUTICS, INC., San Francisco, CA (US);
Abstract
Described herein are binding proteins that specifically bind to human CD33, and in particular to bispecific binding proteins that specifically bind to human CD33 and human CD3. Also described herein are bispecific tandem diabodies that bind to CD33 and CD33, and their uses for immunotherapy of CD33cancers, diseases and conditions such as acute myeloid leukemia (AML).