The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 2015

Filed:

Mar. 18, 2014
Applicant:

Richard B. Thompson, Baltimore, MD (US);

Inventors:

Richard B. Thompson, Baltimore, MD (US);

Evgenia Matveeva, Rockville, MD (US);

Carol Fierke, Ann Arbor, MI (US);

Leslie Bourne, Coatesville, PA (US);

Graham Franke, Baltimore, MD (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/66 (2006.01); G01N 33/542 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/66 (2013.01); G01N 33/542 (2013.01); G01N 2333/988 (2013.01);
Abstract

A method for determining metal ions, both qualitatively and quantitatively, is disclosed. The method utilizes emission from fluorescence resonance energy transfer from a luciferase-carbonic anhydrase conjugate or fusion protein to an acceptor ligand in the presence of metal ion bound to the protein to measure free metal ion concentrations down to picomolar concentration ranges. The method is relatively insensitive to contaminants, and so can be used to measure metal ion concentrations in cells, body fluids or environmental samples without extensive sample preparation.


Find Patent Forward Citations

Thompson, Richard. (2015). Bioluminescent metal ion assay (U.S. Patent No. 9193990). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9193990

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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