The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 2015

Filed:

Nov. 21, 2014
Applicant:

Xencor, Inc., Monrovia, CA (US);

Inventors:

Gregory Alan Lazar, Indianapolis, IN (US);

Arthur Chirino, Camarillo, CA (US);

Wei Dang, Pasadena, CA (US);

John Desjarlais, Pasadena, CA (US);

Stephen K. Doberstein, San Francisco, CA (US);

Robert J. Hayes, Radnor, PA (US);

Sher Bahadur Karki, Santa Monica, CA (US);

Omid Vafa, Monrovia, CA (US);

Assignee:

Xencor, Inc., Monrovia, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 21/08 (2006.01); A61K 39/395 (2006.01); C07K 16/32 (2006.01); C07K 16/28 (2006.01); C07K 16/22 (2006.01); C07K 16/42 (2006.01); C07K 1/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); A61K 39/395 (2013.01); A61K 39/3955 (2013.01); A61K 39/39566 (2013.01); C07K 16/00 (2013.01); C07K 16/22 (2013.01); C07K 16/2863 (2013.01); C07K 16/2875 (2013.01); C07K 16/2887 (2013.01); C07K 16/2893 (2013.01); C07K 16/2896 (2013.01); C07K 16/4291 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/52 (2013.01); C07K 2317/72 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.


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