The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2015
Filed:
Dec. 03, 2012
Applicant:
Chengdu Di'ao Pharmaceutical Group Co., Ltd., Chengdu, CN;
Inventors:
Jianxin Ji, Chengdu, CN;
Na Guo, Chengdu, CN;
Ting Xue, Chengdu, CN;
Bingqiang Kang, Chengdu, CN;
Xinfa Ye, Chengdu, CN;
Xin Chen, Chengdu, CN;
Tao Zhang, Chengdu, CN;
Assignee:
CHENGDU DI'AO PHARMACEUTICAL GROUP CO., LTD., High-Tech Devlopment Zone, Chengdu, CN;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 237/32 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); A61K 31/502 (2006.01); A61K 31/5025 (2006.01); C07D 401/12 (2006.01); C07D 407/14 (2006.01); C07D 409/14 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 237/32 (2013.01); A61K 31/502 (2013.01); A61K 31/5025 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 407/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01);
Abstract
Disclosed are a phthalic hydrazide (phthalazine ketone) compound, and a pharmaceutical composition comprising the same. As a DNA repair enzyme poly (ADP-ribozyme) polymerase inhibitor, the compound and the pharmaceutical composition can effectively treat diseases involving PARP enzymatic activity, including cancer, neural degenerative diseases, inflammation and the like.