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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9162161 B1

PDFFull Text
Date of Patent:
Oct. 20, 2015

Filed:

Mar. 29, 2011

Filler for affinity chromatography

Applicants:

Kouji Tamori, Tokyo, JP;

Takayoshi Abe, Tokyo, JP;

Yusuke Okano, Tokyo, JP;

Masaki Momiyama, Tokyo, JP;

Hiroshi Kawai, Tokyo, JP;

Satoshi Hyugaji, Tokyo, JP;

Tomonori Shiotani, Tokyo, JP;

Kazuhiro Ikkyu, Tokyo, JP;

Yong Wang, Tokyo, JP;

Inventors:

Kouji Tamori, Tokyo, JP;

Takayoshi Abe, Tokyo, JP;

Yusuke Okano, Tokyo, JP;

Masaki Momiyama, Tokyo, JP;

Hiroshi Kawai, Tokyo, JP;

Satoshi Hyugaji, Tokyo, JP;

Tomonori Shiotani, Tokyo, JP;

Kazuhiro Ikkyu, Tokyo, JP;

Yong Wang, Tokyo, JP;

Assignee:

JSR CORPORATION, Tokyo, JP;

Attorney:

Oblon, McClelland, Maier & Neustadt, L.L.P.

Primary Examiner:

Kara Boyle

Int. Cl.
CPC ...
B01D 15/04 (2006.01); B01D 15/08 (2006.01); B01D 15/38 (2006.01); C08F 8/00 (2006.01); C08F 220/26 (2006.01); B01J 20/26 (2006.01); B01J 20/286 (2006.01);
U.S. Cl.
CPC ...
B01D 15/3804 (2013.01); B01J 20/265 (2013.01); B01J 20/286 (2013.01); C08F 8/00 (2013.01); C08F 220/26 (2013.01); Y10T 428/2982 (2015.01);
Abstract

Provided is a filler for affinity chromatography having a high dynamic binding capacity for proteins and having excellent alkali resistance and storage stability. The filler for affinity chromatography of the present invention comprises a porous particle consisting of a copolymer of 40 parts to 99.5 parts by mass of (M-1) a methacryloyl group-containing vinyl monomer that contains a hydroxyl group and does not contain an epoxy group, 0.5 parts to 30 parts by mass of (M-2) an epoxy group-containing vinyl monomer, 0 parts to 59.5 parts by mass of (M-3) a methacryloyl group-containing vinyl monomer which is other than the monomers (M-1) and (M-2), and 0 parts to 25 parts by mass of (M-4) a vinyl monomer other than the monomers (M-1), (M-2) and (M-3) (with the proviso that the total amount of the contents of (M-1), (M-2), (M-3) and (M-4) is 100 parts by mass); ring-opened epoxy group obtainable by ring-opening of epoxy group that is contained in the copolymer; and ligand that is bound to the porous particle.

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