The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2015
Filed:
Jan. 16, 2009
Alan Marc Kleinfeld, La Jolla, CA (US);
Andrew Henry Huber, Encinitas, CA (US);
James Patrick Kampf, San Diego, CA (US);
Thomas Kwan, San Diego, CA (US);
Baolong Zhu, San Diego, CA (US);
Alan Marc Kleinfeld, La Jolla, CA (US);
Andrew Henry Huber, Encinitas, CA (US);
James Patrick Kampf, San Diego, CA (US);
Thomas Kwan, San Diego, CA (US);
Baolong Zhu, San Diego, CA (US);
Other;
Abstract
A method for high throughput discovery of proteins fluorescently labeled at a cysteine residue and that undergo a change in fluorescence ratio at 2 wavelengths upon binding an unbound analyte is described. Probes are disclosed which are labeled at a cysteine residue and also probes labeled at both cysteine and lysine with two different fluorophores. These probes are useful for characterization and measurement of hydrophobic species in a fluid sample, particularly characterization and measurement of levels of unbound free fatty acids. A profile of unbound free fatty acids can be determined for an individual which can be used to determine the individual's relative risk for disease.