The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2015

Filed:

Mar. 24, 2015
Applicant:

Oilcrops Research Institute of Chinese Academy of Agriculture Sciences, Wuhan, Hubei, CN;

Inventors:

Peiwu Li, Hubei, CN;

Ting He, Hubei, CN;

Qi Zhang, Hubei, CN;

Zhaowei Zhang, Hubei, CN;

Xiaoxia Ding, Hubei, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); A61K 51/10 (2006.01); G01N 33/569 (2006.01); C07K 16/14 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56961 (2013.01); C07K 16/14 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); G01N 2333/38 (2013.01); G01N 2469/10 (2013.01);
Abstract

Aflatoxin M1 nanobody 2014AFM-G2 has the amino acid sequence of SEQ ID NO:7, and is encoded by the gene sequence of SEQ ID NO:8. The aflatoxin M1 nanobody 2014AFM-G2 obtained via screening has the properties of tolerance to organic reagents, tolerance to high temperature, tolerance to acids and bases and the like, and good stability. The aflatoxin M1 nanobody 2014AFM-G2 has 50% inhibiting concentration ICto aflatoxin M1 of 0.208 ng/mL, and has cross reaction rates with aflatoxin B1, B2, G1, G2 are 9.43%, 5.93%, 4.87% and 6.17%, respectively.


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