The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2015
Filed:
Dec. 05, 2008
Takanori Nakamura, Minamisaitama-gun, JP;
Atsushi Miyamura, Minamisaitama-gun, JP;
Taito Nishino, Tokyo, JP;
Norihisa Ishiwata, Minamisaitama-gun, JP;
Katsuaki Miyaji, Funabashi, JP;
Takanori Nakamura, Minamisaitama-gun, JP;
Atsushi Miyamura, Minamisaitama-gun, JP;
Taito Nishino, Tokyo, JP;
Norihisa Ishiwata, Minamisaitama-gun, JP;
Katsuaki Miyaji, Funabashi, JP;
Nissan Chemical Industries, Ltd., Tokyo, JP;
Abstract
An object of the present invention is to expand CD34cells ex vivo efficiently in a short term using a biologically safe and inexpensively obtainable low molecular weight compound. A still another object of the present invention is to provide an expansion agent for CD34cells useful for treatment of various hematopoietic disorders caused by dysfunctional hematopoietic stem cells and/or hematopoietic progenitor cells. A method for expanding CD34cells, which comprises culturing CD34cells ex vivo in the presence of a compound represented by the formula (I) (wherein A, B, L, L, L, L, R, R, R, X and Y are defined in the description), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof.