The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2015
Filed:
Jan. 30, 2009
Cheryl Winkler, Gaithersburg, MD (US);
George Nelson, Thurmont, MD (US);
Jeffrey B. Kopp, Bethesda, MD (US);
Michael W. Smith, Jefferson, MD (US);
Randall Johnson, Frederick, MD (US);
Cheryl Winkler, Gaithersburg, MD (US);
George Nelson, Thurmont, MD (US);
Jeffrey B. Kopp, Bethesda, MD (US);
Michael W. Smith, Jefferson, MD (US);
Randall Johnson, Frederick, MD (US);
Abstract
Methods for determining the genetic predisposition of a human subject to developing renal disease, such as focal segmental glomerulosclerosis (FSGS) or end-stage kidney disease are provided herein. These methods include methods for detecting renal disease, or determining the risk of developing renal disease in a human subject, such as a subject of African ancestry. The methods utilize the detection of one or more haplotype blocks comprising at least two tag single nucleotide polymorphisms (SNPs) in a non-coding region of a MYH9 gene or detecting the presence of at least one tag SNP in a non-coding region of a MYH9 gene. An array for detecting a genetic predisposition to renal disease using probes complementary to the tag SNPs in the non-coding region of the MYH9 gene are also disclosed.