The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2015

Filed:

Aug. 09, 2012
Applicants:

W. Jason Cummings, Bellevue, WA (US);

Munehisa Yabuki, Seattle, WA (US);

John B. Leppard, Mukilteo, WA (US);

Christi L. Wood, Snohomish, WA (US);

Nancy Maizels, Seattle, WA (US);

Daniel S. Allison, Lake Forest Park, WA (US);

Larry W. Tjoelker, Kirkland, WA (US);

Inventors:

W. Jason Cummings, Bellevue, WA (US);

Munehisa Yabuki, Seattle, WA (US);

John B. Leppard, Mukilteo, WA (US);

Christi L. Wood, Snohomish, WA (US);

Nancy Maizels, Seattle, WA (US);

Daniel S. Allison, Lake Forest Park, WA (US);

Larry W. Tjoelker, Kirkland, WA (US);

Assignee:

Omeros Corporation, Seattle, WA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 45/06 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 45/06 (2013.01); A61K 47/48469 (2013.01); A61K 47/48561 (2013.01); C07K 16/2863 (2013.01); C07K 16/2896 (2013.01); C07K 2317/23 (2013.01); C07K 2317/24 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present invention relates generally to anti-FZD10 antibodies and to methods of using anti-FZD10 antibodies. In particular, the anti-FZD10 antibodies described herein are useful for altering one or more of survival, replication, differentiation and epithelial-to-mesenchymal cell transition of embryonic stem cells and/or for the treatment of diseases, such as a variety of cancers, associated with expression of FZD10, including as stand-alone therapies and in combination therapies with other agents.


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