The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2015

Filed:

Jun. 16, 2011
Applicants:

Xuezhi Yin, Jiangsu, CN;

Bing Wang, Jiangsu, CN;

Ying Ji, Jiangsu, CN;

Mingyuan Liu, Jiangsu, CN;

Inventors:

Xuezhi Yin, Jiangsu, CN;

Bing Wang, Jiangsu, CN;

Ying Ji, Jiangsu, CN;

Mingyuan Liu, Jiangsu, CN;

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 41/22 (2006.01);
U.S. Cl.
CPC ...
C07C 41/22 (2013.01); C07C 41/22 (2013.01); C07C 43/174 (2013.01); C07C 43/225 (2013.01);
Abstract

Disclosed are methods for preparation of two pharmaceutical intermediates (I, II) of Aliskiren, said intermediates are obtained by reacting compound of formula I or II and tribromophosphorus oxide. The method replaces the method in the prior art which is using column chromatopraphy to produce the compounds I and II, and overcomes the defect that the method in the prior art hardly carry out in a large-scale industrial production. The product can be purified by recrystallization or vacuum distillation, and the chemical purity of the product is good.


Find Patent Forward Citations

Yin, Xuezhi. (2015). Methods for preparation of pharmaceutical intermediates of aliskiren (U.S. Patent No. 9079839). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9079839

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