The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2015
Filed:
Jan. 23, 2014
University of British Columbia, Vancouver, CA;
Elizabeth M. Simpson, Vancouver, CA;
Wyeth W. Wasserman, Vancouver, CA;
Robert A. Holt, Vancouver, CA;
Steven J. Jones, Vancouver, CA;
Daniel Goldowitz, Vancouver, CA;
Elodie Portales-Casamar, Vancouver, CA;
Cletus D'Souza, Vancouver, CA;
Vikramjit Chopra, Vancouver, CA;
Charles de Leeuw, Vancouver, CA;
THE UNIVERSITY OF BRITISH COLUMBIA, Vancouver, B.C., CA;
Abstract
Isolated polynucleotides comprising a DCX mini-promoters are provided. The mini-promoter may be operably linked to an expressible sequence, e.g. reporter genes, genes encoding a polypeptide of interest, regulatory RNA sequences such as miRNA, siRNA, anti-sense RNA, etc., and the like. In some embodiments a cell comprising a stable integrant of an expression vector is provided, which may be integrated in the genome of the cell. The promoter may also be provided in a vector, for example in combination with an expressible sequence. The polynucleotides find use in a method of expressing a sequence of interest, e.g. for identifying or labeling cells, monitoring or tracking the expression of cells, gene therapy, etc.