The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2015
Filed:
Jun. 06, 2012
Applicants:
Holger Gruell, Eindhoven, NL;
Sander Langereis, Mierlo, NL;
Johan Lub, Valkenswaard, NL;
Inventors:
Assignee:
Koninklijke Philips N.V., Eindhoven, NL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/12 (2006.01); A61K 49/18 (2006.01); A61K 47/14 (2006.01); C07C 69/28 (2006.01); C07C 69/33 (2006.01); C07C 69/708 (2006.01); A61K 9/127 (2006.01); A61K 41/00 (2006.01); A61K 49/08 (2006.01); A61K 49/10 (2006.01);
U.S. Cl.
CPC ...
A61K 47/14 (2013.01); C07C 69/28 (2013.01); C07C 69/33 (2013.01); C07C 69/708 (2013.01); A61K 9/1273 (2013.01); A61K 41/0028 (2013.01); A61K 49/085 (2013.01); A61K 49/10 (2013.01); A61K 49/103 (2013.01); A61K 49/106 (2013.01); A61K 49/1812 (2013.01); A61K 9/1272 (2013.01);
Abstract
Disclosed are lipidomimetic compounds of formula I (I) wherein: G represents a group satisfying formula II: HO—CH—{CH(OH)—CH-0}-CH—{C(=0)-0-CH})— formula II each n independently is an integer from 1-30; m is an integer from 1-10; q is 0 or 1. These compounds can be added to the lipid bilayer of thermosensitive liposomes, for the purpose of aiding in the prevention of leakage of the liposomes' contents at 37° C., and retarding clearance from circulation.