The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2015

Filed:

Mar. 23, 2011
Applicants:

Kouji Tamori, Minato-ku, JP;

Tetsuo Fukuta, Minato-ku, JP;

Masaaki Miyaji, Minato-ku, JP;

Yong Wang, Minato-ku, JP;

Takayoshi Abe, Minato-ku, JP;

Yusuke Okano, Minato-ku, JP;

Masaki Momiyama, Minato-ku, JP;

Takahiro Kawai, Minato-ku, JP;

Inventors:

Kouji Tamori, Minato-ku, JP;

Tetsuo Fukuta, Minato-ku, JP;

Masaaki Miyaji, Minato-ku, JP;

Yong Wang, Minato-ku, JP;

Takayoshi Abe, Minato-ku, JP;

Yusuke Okano, Minato-ku, JP;

Masaki Momiyama, Minato-ku, JP;

Takahiro Kawai, Minato-ku, JP;

Assignee:

JSR CORPORATION, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 1/22 (2006.01); B01D 15/38 (2006.01); B01J 20/286 (2006.01); B01J 20/288 (2006.01); B01J 20/32 (2006.01);
U.S. Cl.
CPC ...
C07K 1/22 (2013.01); B01D 15/3804 (2013.01); B01J 20/286 (2013.01); B01J 20/288 (2013.01); B01J 20/3274 (2013.01); C07K 2317/10 (2013.01); B01J 20/3219 (2013.01);
Abstract

Provided are a filler for affinity chromatography which has excellent alkali resistance, and a method for isolating immunoglobulin. The filler for affinity chromatography is a filler in which a protein represented by the following formula (1) is immobilized on a carrier.R—R  (1) wherein R represents an amino acid sequence consisting of 4 to 300 amino acid residues containing a region consisting of 4 to 20 contiguous histidine residues; and Rrepresents an amino acid sequence capable of binding to immunoglobulin, the amino acid sequence consisting of 50 to 500 amino acid residues containing Z domain of Protein A or a fragment thereof, or a variant thereof, provided that the R binds to C-terminus or N-terminus of the R.


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