The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2015
Filed:
Dec. 13, 2006
Alexander F. Zabudkin, Donetsk, UA;
Victor Matvienko, Donetsk, UA;
Alexey Matveev, Donetsk, UA;
Aleksandr M. Itkin, San Diego, CA (US);
Alexander F. Zabudkin, Donetsk, UA;
Victor Matvienko, Donetsk, UA;
Alexey Matveev, Donetsk, UA;
Aleksandr M. Itkin, San Diego, CA (US);
SOLUX CORPORATION, San Diego, CA (US);
Abstract
A method of preparing the anthracyclin carminomycin using a starting material comprising daunorubicin. The method comprises reacting daunorubicin or N-protected daunorubicin with soft Lewis acids for the demethylation of the 4-methoxy group, resulting in a reaction mass. The reaction mass is treated with an aqueous solution of a strong organic acid or a mineral acid. After decomposition of the resulting carminomycin and Lewis acids reactive complex, the reaction mass is extracted using a water insoluble organic solvent. As a result, carminomycin is extracted as a base.