The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2015
Filed:
Sep. 08, 2009
Holger Gruell, Eindhoven, NL;
Anke DE Vries, Eindhoven, NL;
Sander Langereis, Mierlo, NL;
Johan Lub, Valkenswaard, NL;
Erica M. G. Aussems-custers, Helmond, NL;
Holger Gruell, Eindhoven, NL;
Anke De Vries, Eindhoven, NL;
Sander Langereis, Mierlo, NL;
Johan Lub, Valkenswaard, NL;
Erica M. G. Aussems-Custers, Helmond, NL;
Koninklijke Philips N.V., Eindhoven, NL;
Abstract
Described are amphiphilic polymers that are provided with chelating moieties. The amphiphilic polymers are block copolymers comprising a hydrophilic block and a hydrophobic block, with the chelating moieties linked to the end-group of the hydrophilic block. The disclosed polymers are capable of self-assembly into structures such as micelles and polymersomes. With suitable metals present in the form of coordination complexes with 5 the chelating moieties, the chelating amphiphilic polymers of the invention are suitable for use in various imaging techniques requiring metal labeling, such as MRI (T 1/T 2 weighted contrast agents or CEST contrast agents) SPECT, PET or Spectral CT.