The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2015
Filed:
Dec. 07, 2010
John P. Toscano, Glen Arm, MD (US);
Art Sutton, Baltimore, MD (US);
Vincent J. Kalish, Annapolis, MD (US);
Frederick Arthur Brookfield, Abingdon, GB;
Stephen Martin Courtney, Abingdon, GB;
Lisa Marie Frost, Abingdon, GB;
John P. Toscano, Glen Arm, MD (US);
Art Sutton, Baltimore, MD (US);
Vincent J. Kalish, Annapolis, MD (US);
Frederick Arthur Brookfield, Abingdon, GB;
Stephen Martin Courtney, Abingdon, GB;
Lisa Marie Frost, Abingdon, GB;
Cardioxyl Pharmaceuticals, Inc., Chapel Hill, NC (US);
The Johns Hopkins University, Baltimore, MD (US);
Abstract
The invention provides certain bis-acylated hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the invention provides methods of using such compounds or pharmaceutical compositions for treating, preventing, or delaying the onset and/or develop of a disease or condition. In some embodiments, the disease or condition is selected from cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy.