The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2015
Filed:
Jan. 20, 2006
Applicant:
James A. Williams, Lincoln, NE (US);
Inventor:
James A. Williams, Lincoln, NE (US);
Assignee:
Nature Technology Corporation, Lincoln, NE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/87 (2006.01); A61K 39/00 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A61K 39/00 (2013.01); A61K 2039/53 (2013.01); C12N 15/85 (2013.01); C12N 2800/106 (2013.01); C12N 2800/107 (2013.01); C12N 2830/15 (2013.01);
Abstract
Improved DNA vaccine plasmids are disclosed. The improved plasmids eliminate all extraneous sequences, and have superior eukaryotic expression, improved yield and stability during bacterial production, facilitate flexible targeting of antigens to various intracellular destinations, and novel RNA-based functionality. These vectors are utilized in novel immunization methods wherein combinations of immunostimulatory DNA vaccine plasmids that target antigens to various intracellular destinations are used to elicit improved immune response.