The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2015

Filed:

Mar. 11, 2014
Applicant:

Arqule, Inc., Woburn, MA (US);

Inventors:

Nivedita Namdev, Westford, MA (US);

Jianqiang Wang, Acton, MA (US);

Mark Ashwell, Carlisle, MA (US);

Audra Dalton, Revere, MA (US);

Jason Hill, Auburndale, MA (US);

Eugene Kelleher, Wellesley, MA (US);

Jeffrey Link, Londonderry, NH (US);

Rocio Palma, North Andover, MA (US);

Sudharshan Eathiraj, Shrewsbury, MA (US);

Neil Westlund, Groton, MA (US);

Hui Wu, Malden, MA (US);

Rui-Yang Yang, Lexington, MA (US);

Assignee:

ArQule Inc., Woburn, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/14 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); C07D 491/107 (2013.01);
Abstract

The present invention relates to substituted tricyclic pyrazolo-pyrimidine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted tricyclic pyrazolo-pyrimidine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.


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