The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2015
Filed:
May. 28, 2010
Applicants:
Hideyuki Okano, Tokyo, JP;
Yohei Okada, Tokyo, JP;
Shinya Yamanaka, Kyoto, JP;
Kyoko Miura, Kyoto, JP;
Inventors:
Hideyuki Okano, Tokyo, JP;
Yohei Okada, Tokyo, JP;
Shinya Yamanaka, Kyoto, JP;
Kyoko Miura, Kyoto, JP;
Assignee:
Kyoto University, Kyoto, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/05 (2006.01); C12N 15/00 (2006.01); C12N 5/074 (2010.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6881 (2013.01); C12N 5/0696 (2013.01); C12N 2510/00 (2013.01); C12Q 2600/158 (2013.01);
Abstract
To efficiently identify and select a clone from clones of induced pluripotent stem cells (iPS cell) having low tumor formation rate in vivo when allowed to differentiate and transplanted in a living body, iPS cells of the clones are induced to differentiate, undifferentiated cells among the cells after the induction of differentiation are detected, and a clone having the content of the undifferentiated cell below a control is selected.