The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2015
Filed:
May. 16, 2012
Thomas Tuschl, New York, NY (US);
Mariana Lagos-quintana, Berlin, DE;
Winfried Lendeckel, Hohengandern, DE;
Jutta Dammann, Vienna, AT;
Reinhard Rauhut, Goettingen, DE;
Thomas Tuschl, New York, NY (US);
Mariana Lagos-Quintana, Berlin, DE;
Winfried Lendeckel, Hohengandern, DE;
Jutta Dammann, Vienna, AT;
Reinhard Rauhut, Goettingen, DE;
Abstract
In, lin-4 and let-7 encode 22- and 21-nucleotide RNAs, respectively, that function as key regulators of developmental timing. Because the appearance of these short RNAs is regulated during development, they are also referred to as 'small temporal RNAs' (stRNAs). We show that many more 21- and 22-nt expressed RNAs, termed microRNAs, (miRNAs), exist in invertebrates and vertebrates, and that some of these novel RNAs, similar to let-7 stRAN, are also highly conserved. This suggests that sequence-specific post-transcriptional regulatory mechanisms mediated by small RNAs are more general than previously appreciated.