The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2015
Filed:
Feb. 04, 2009
Applicants:
A. Thomas Look, North Reading, MA (US);
Samuel Sidi, New York, NY (US);
Inventors:
A. Thomas Look, North Reading, MA (US);
Samuel Sidi, New York, NY (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/407 (2006.01); A61P 35/00 (2006.01); C12Q 1/37 (2006.01); C12Q 1/68 (2006.01); G01N 33/574 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/574 (2013.01); A61K 49/0008 (2013.01); G01N 2333/4704 (2013.01); G01N 2333/96413 (2013.01); G01N 2800/52 (2013.01);
Abstract
The invention describes methods that are useful for treating cancer by administering a Chk1 inhibitor which can induce apoptosis in p53-defective cells when combined with a chemotherapy and/or radiotherapy. Methods for screening candidates for a Chk1 inhibitor-based cancer treatment regimen are also described.