The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2015
Filed:
May. 17, 2013
Kaneka Corporation, Osaka, JP;
Takahiro Ohishi, Takasago, JP;
Hirokazu Nanba, Takasago, JP;
Masanobu Sugawara, Takasago, JP;
Masashi Izumida, Takasago, JP;
Tatsuya Honda, Takasago, JP;
Kohei Mori, Takasago, JP;
Satohiro Yanagisawa, Takasago, JP;
Nobuo Nagashima, Takasago, JP;
Kenji Inoue, Takasago, JP;
Kaneka Corporation, Osaka, JP;
Abstract
The present invention provides a simple industrial process for producing an L- or D-optically active α-methylcysteine derivative or its salt, which is a useful pharmaceutical intermediate, from readily available, inexpensive raw materials. In a process for producing an L- or D-optically active α-methylcysteine derivative or its salt, a racemic N-carbamoyl-α-methylcysteine derivative or its salt is D-selectively cyclized with hydantoinase to produce a D-5-methyl-5-thiomethylhydantoin derivative or its salt and an N-carbamoyl-α-methyl-L-cysteine derivative or its salt, which are then subjected to deprotection of the amino group and the sulfur atom, and hydrolysis.