The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Dec. 22, 2010
Applicants:

Colin Hill, Cork, IE;

Paul Cotter, Cork, IE;

Paul R. Ross, Cork, IE;

Desmond Field, Cork, IE;

Inventors:

Colin Hill, Cork, IE;

Paul Cotter, Cork, IE;

Paul R. Ross, Cork, IE;

Desmond Field, Cork, IE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61K 38/12 (2006.01); C12N 15/00 (2006.01); C07K 14/315 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/315 (2013.01); A61K 38/00 (2013.01);
Abstract

A Nisin derivative or variant, comprising an amino acid substitution at amino acid position 29 in the amino acid sequence. The Nisin derivative exhibits enhanced antimicrobial activity when compared to wild type Nisin. The Nisin derivative has an application as a natural food additive and as a therapeutic agent.


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