The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2015

Filed:

Oct. 05, 2012
Applicant:

Trustees of Boston University, Boston, MA (US);

Inventors:

Kenneth Walsh, Carlisle, MA (US);

Yuichi Oshima, Toyonaka, JP;

Noriyuki Ouchi, Nagoya, JP;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61P 9/10 (2006.01); A61P 39/06 (2006.01); A61K 38/17 (2006.01); C07K 14/545 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); Y10S 514/824 (2013.01); Y10S 514/866 (2013.01);
Abstract

Described herein are methods and compositions related to the discovery that the Follistatin-like 1 protein (Fstl-1) has metabolic and cardioprotective effects in vivo. Fstl-1 and portions and derivatives or variants thereof can be used to treat or prevent metabolic diseases or disorders and to treat or prevent cardiac damage caused by interrupted cardiac muscle blood supply.


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