The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2015

Filed:

Nov. 05, 2010
Applicants:

Hsueh-chia Chang, Granger, IN (US);

Peter Mushenheim, Cuyahoga Falls, OH (US);

Sagnik Basuray, Mishawaka, IN (US);

Gilad Yossifon, Mazkeret-Batia, IL;

Satyajyoti Senapati, Mishawaka, IN (US);

Inventors:

Hsueh-Chia Chang, Granger, IN (US);

Peter Mushenheim, Cuyahoga Falls, OH (US);

Sagnik Basuray, Mishawaka, IN (US);

Gilad Yossifon, Mazkeret-Batia, IL;

Satyajyoti Senapati, Mishawaka, IN (US);

Assignee:

University of Notre Dame du Lac, Notre Dame, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 27/26 (2006.01); G01N 33/50 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
G01N 33/48721 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/686 (2013.01);
Abstract

A microchamber electrochemical cell and method of using the cell for performing quantitative analysis of various charged macromolecules is presented. The microchamber electrochemical cell includes a substrate, opposing electrodes and at least one nanoslot. The substrate is configured to define a pair of opposing fluid reservoirs. The pair of opposing electrodes are respectively positioned within the opposing fluid reservoirs. Each nanoslot is configured to fluidly connect the opposing fluid reservoirs together. The opposing fluid reservoirs of the microchamber electrochemical cell are fluidly connected to each other only through each nanoslot. Each nanoslot is physically restricted to less than 500 nanometers. One method includes the steps of coupling, filling, measuring, obtaining, performing and preparing.


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