The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2015

Filed:

Sep. 23, 2009
Applicants:

Muthiah Manoharan, Cambridge, MA (US);

Kallanthottathil G. Rajeev, Cambridge, MA (US);

Takeshi Yamada, Cambridge, MA (US);

David Butler, Cambridge, MA (US);

Narayanannair K. Jayaprakash, Cambridge, MA (US);

Muthusamy Jayaraman, Cambridge, MA (US);

Shigeo Matsuda, Cambridge, MA (US);

Rajendra K. Pandey, Cambridge, MA (US);

Chang Geng Peng, Cambridge, MA (US);

Inventors:

Muthiah Manoharan, Cambridge, MA (US);

Kallanthottathil G. Rajeev, Cambridge, MA (US);

Takeshi Yamada, Cambridge, MA (US);

David Butler, Cambridge, MA (US);

Narayanannair K. Jayaprakash, Cambridge, MA (US);

Muthusamy Jayaraman, Cambridge, MA (US);

Shigeo Matsuda, Cambridge, MA (US);

Rajendra K. Pandey, Cambridge, MA (US);

Chang Geng Peng, Cambridge, MA (US);

Assignee:

Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); H04L 29/06 (2006.01); C07H 21/00 (2006.01); H04L 29/08 (2006.01);
U.S. Cl.
CPC ...
H04L 65/602 (2013.01); C07H 21/00 (2013.01); H04L 67/36 (2013.01);
Abstract

The invention features compounds of formula I or II: In one embodiment, the invention relates compounds and processes for conjugating ligand to oligonucleotide. The invention further relates to methods for treating various disorders and diseases such as viral infections, bacterial infections, parasitic infections, cancers, allergies, autoimmune diseases, immunodeficiencies and immunosuppression.


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