The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2015
Filed:
May. 20, 2011
Rebecca A. Zangmeister, Gaithersburg, MD (US);
Germarie Sanchez-pomales, Gaithersburg, MD (US);
Todd A. Morris, Selinsgrove, PA (US);
Michael J. Tarlov, Bethesda, MD (US);
Rebecca A. Zangmeister, Gaithersburg, MD (US);
Germarie Sanchez-Pomales, Gaithersburg, MD (US);
Todd A. Morris, Selinsgrove, PA (US);
Michael J. Tarlov, Bethesda, MD (US);
The United States of America as represented by the Secretary of Commerce, Washington, DC (US);
The National Institute of Standards and Technology, Gaithersburg, MD (US);
Abstract
A method of characterizing glycans attached to glycoproteins is disclosed herein. The method comprises a first step of immobilizing the glycoproteins on colloidal particles forming glycoprotein/colloidal particles. The glycans on the glycoproteins may then be characterized, for example the composition and/or structure of glycans may be characterized or the glycans attached to proteins may be identified. Characterization may be accomplished by either binding the glycoprotein/colloidal particles with one or more binding agents and assessing the aggregation of the glycoprotein/colloidal particles or by cleaving glycans from the glycoprotein/colloidal particles with a cleaving agent and analyzing the glycans.