The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2015
Filed:
Mar. 26, 2012
Herman O. Sintim, Bowie, MD (US);
William E. Bentley, Annapolis, MD (US);
Varnika Roy, College Park, MD (US);
Jacqueline Smith, District Heights, MD (US);
Reza Ghodssi, Silver Spring, MD (US);
Mariana Tsacoumis Meyer, Baltimore, MD (US);
Herman O. Sintim, Bowie, MD (US);
William E. Bentley, Annapolis, MD (US);
Varnika Roy, College Park, MD (US);
Jacqueline Smith, District Heights, MD (US);
Reza Ghodssi, Silver Spring, MD (US);
Mariana Tsacoumis Meyer, Baltimore, MD (US);
University of Maryland, College Park, College Park, MD (US);
Abstract
Provided are compositions and methods for modulating quorum sensing in microbes. The compounds are AI-2 analogs and as such have structures similar to 4,5-dihydroxy-2,3-pentanedione that can act as agonists/antagonists of quorum sensing. The compounds are useful for modulating quorum sensing in bacteria and can be used in methods for prophylaxis or therapy of bacterial infections and for reduction of biofilms.