The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 10, 2015

Filed:

Aug. 22, 2012
Applicants:

Jie Yang, Foster City, CA (US);

Xiyun Zhang, Fremont, CA (US);

Jungjoo Yoon, Foster City, CA (US);

Kripa Rao, San Mateo, CA (US);

John H. Grate, Los Altos, CA (US);

David Elgart, San Mateo, CA (US);

Dipnath Baidyaroy, Fremont, CA (US);

Inventors:

Jie Yang, Foster City, CA (US);

Xiyun Zhang, Fremont, CA (US);

Jungjoo Yoon, Foster City, CA (US);

Kripa Rao, San Mateo, CA (US);

John H. Grate, Los Altos, CA (US);

David Elgart, San Mateo, CA (US);

Dipnath Baidyaroy, Fremont, CA (US);

Assignee:

Codexis, Inc., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/14 (2006.01); C12P 7/40 (2006.01); C12P 7/56 (2006.01); C12P 19/00 (2006.01); C12P 7/10 (2006.01); C12N 9/30 (2006.01); C12N 9/42 (2006.01);
U.S. Cl.
CPC ...
C12P 7/10 (2013.01); C12P 19/14 (2013.01); C12N 9/242 (2013.01); C12N 9/2434 (2013.01); C12Y 302/01021 (2013.01); C12Y 302/01091 (2013.01); C12N 9/2437 (2013.01); C12N 9/2445 (2013.01); Y02E 50/16 (2013.01);
Abstract

The present invention provides various GH61 protein variants comprising various amino acid substitutions. The GH61 protein variants have an improved ability to synergize with cellulase enzymes, thereby increasing the yield of fermentable sugars obtained by saccharification of biomass. In some embodiments, sugars obtained from saccharification are fermented to produce numerous end-products, including but not limited to alcohol.


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