The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Apr. 24, 2009
Applicants:

Joseph Desimone, Chapel Hill, NC (US);

Matthew Parrott, Carrboro, NC (US);

Andrew Murphy, Cary, NC (US);

Robby A. Petros, Denton, TX (US);

Inventors:

Joseph DeSimone, Chapel Hill, NC (US);

Matthew Parrott, Carrboro, NC (US);

Andrew Murphy, Cary, NC (US);

Robby A. Petros, Denton, TX (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/74 (2006.01); C07F 7/18 (2006.01);
U.S. Cl.
CPC ...
C07F 7/184 (2013.01);
Abstract

The present invention provides compounds that will degrade under specified conditions, methods of using such compounds, and compositions comprising such compounds. The degradable compounds of the invention may be characterized by the labile —Si-A-C— groups present in the compounds (A representing an atom, such as O, N, or S, or a group, such as C═O). The compounds may be incorporated into a composition that further may include a polymeric matrix and/or a cargo component. A wide variety of cargo components may also be used in the present invention. In particular embodiments, the cargo component comprises a drug or other therapeutic agent. Accordingly, the invention particularly provides pharmaceutical formulations and methods of delivering a drug or other therapeutic material.


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