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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8937158 B1

PDFFull Text
Date of Patent:
Jan. 20, 2015

Filed:

Aug. 20, 2007

Fc variants with increased affinity for fcγriic

Applicants:

Gregory Alan Lazar, Los Angeles, CA (US);

Wei Dang, Pasadena, CA (US);

John R. Desjarlais, Pasadena, CA (US);

Sher Bahadur Karki, Pasadena, CA (US);

Omid Vafa, Monrovia, CA (US);

Robert Hayes, Paoli, PA (US);

Inventors:

Gregory Alan Lazar, Los Angeles, CA (US);

Wei Dang, Pasadena, CA (US);

John R. Desjarlais, Pasadena, CA (US);

Sher Bahadur Karki, Pasadena, CA (US);

Omid Vafa, Monrovia, CA (US);

Robert Hayes, Paoli, PA (US);

Assignee:

Xencor, Inc., Monrovia, CA (US);

Attorneys:

Robin M. Silva

Morgan, Lewis & Bockius, LLP

Primary Examiner:

Chun Dahle

Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 21/08 (2006.01); C07K 16/30 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01); C07K 1/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); C07K 16/00 (2013.01); C07K 16/2863 (2013.01); C07K 16/2887 (2013.01); C07K 16/2893 (2013.01); C07K 16/2896 (2013.01); C07K 16/32 (2013.01); A61K 2039/505 (2013.01); C07K 2317/41 (2013.01); C07K 2317/71 (2013.01); C07K 2317/72 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); C07K 2317/34 (2013.01);
Abstract

The present invention relates to Fc variants having increased affinity for FcγRIIc, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Find Patent Forward Citations

Lazar, Gregory. (2015). Fc variants with increased affinity for fcγriic (U.S. Patent No. 8937158). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8937158

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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