The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 20, 2015
Filed:
Mar. 30, 2007
Applicants:
Dennis Sprott, Ottawa, CA;
Dennis M. Whitfield, Ottawa, CA;
Lakshmi Krishnan, Ottawa, CA;
Inventors:
Assignee:
National Research Council of Canada, Ottawa, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 9/127 (2006.01); A61K 39/39 (2006.01); C07H 15/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1272 (2013.01); A61K 39/39 (2013.01); C07H 15/06 (2013.01); A61K 2039/55583 (2013.01); A61K 2039/55594 (2013.01);
Abstract
Archaeal lipid adjuvants are synthesized by chemically coupling various carbohydrates or anionic polar groups to the free hydroxyl(s) of archaeal lipid cores. Chemically stable lipid cores such as saturated archaeol and caldarchaeol are obtained from appropriate Archaea. Archaeosome lipid vesicles are formulated from the synthetic lipids selected to serve as antigen carriers that target antigen-presenting cells and promote an appropriate immune response to the antigen.