The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Aug. 25, 2008
Gregory L. Baker, Haslett, MI (US);
Milton R. Smith, Iii, East Lansing, MI (US);
Xuwei Jiang, Berkeley, CA (US);
Erin B. Vogel, Midland, MI (US);
Gregory L. Baker, Haslett, MI (US);
Milton R. Smith, III, East Lansing, MI (US);
Xuwei Jiang, Berkeley, CA (US);
Erin B. Vogel, Midland, MI (US);
Board of Trustees of Michigan State University, East Lansing, MI (US);
Abstract
Poly(glycolide) polymers are disclosed. The polymers generally include a polymerized alkynyl-substituted glycolide having a polymer backbone with one or more alkynyl groups appended thereto. The alkynyl groups provide reactive sites for further functionalization of the polymer, for example by reaction with azide derivatives (e.g., azide-substituted organic compounds). Alkynyl and azide groups react via the 'click' chemistry mechanism to form functional groups covalently bonded to the polymer via a triazole link. The polymers are biodegradable and can be used to deliver drugs or other therapeutic substances (e.g., large biomolecules such as single strand RNA) at targeted locations in a patient's body and/or at controlled release rates.