The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Feb. 16, 2011
Shinya Yamanaka, Kyoto, JP;
Naoki Goshima, Tokyo, JP;
Momoko Maekawa, Kyoto, JP;
Yoshifumi Kawamura, Tokyo, JP;
Hiromi Mochizuki, Tokyo, JP;
Shinya Yamanaka, Kyoto, JP;
Naoki Goshima, Tokyo, JP;
Momoko Maekawa, Kyoto, JP;
Yoshifumi Kawamura, Tokyo, JP;
Hiromi Mochizuki, Tokyo, JP;
Kyoto University, Kyoto, JP;
National Institute of Advanced Industrial Science and Technology, Tokyo, JP;
Japan Biological Informatics Consortium, Tokyo, JP;
Abstract
Provided are a method of improving the efficiency of establishment of iPS cells, comprising the step of contacting one or more substances selected from the group consisting of members of the GLIS family (e.g., GLIS1) and nucleic acids that encode the same and one or more substances selected from the group consisting of members of the Klf family and nucleic acids that encode the same, with a somatic cell, an iPS cell comprising an exogenous nucleic acid that encodes a member of the GLIS family or a member of the Klf family, that can be obtained by the method, and a method of producing a somatic cell by inducing the differentiation of the iPS cell.