The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2015

Filed:

Apr. 07, 2011
Applicants:

Yoshikazu Ootsuka, Funabashi, JP;

Tomohiro Akeboshi, Funabashi, JP;

Akiko Yamazaki, Funabashi, JP;

Yusuke Iriyama, Funabashi, JP;

Inventors:

Yoshikazu Ootsuka, Funabashi, JP;

Tomohiro Akeboshi, Funabashi, JP;

Akiko Yamazaki, Funabashi, JP;

Yusuke Iriyama, Funabashi, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/06 (2006.01); C12P 17/04 (2006.01); C07F 7/08 (2006.01); C07D 307/33 (2006.01); C07B 53/00 (2006.01); C07D 309/30 (2006.01); C07D 309/32 (2006.01);
U.S. Cl.
CPC ...
C07D 307/33 (2013.01); C07B 53/00 (2013.01); C07D 309/30 (2013.01); C07D 309/32 (2013.01); C07F 7/083 (2013.01); C12P 17/04 (2013.01); C12P 17/06 (2013.01);
Abstract

An acylating agent and a hydrolase are caused to act on a hydroxypyranone represented by formula (I) in a water-containing organic solvent, to thereby produce an acyloxypyranone compound represented by formula (II) (wherein Rrepresents an acyl group). Then, an acetylene organic metal compound represented by formula (III) (wherein Rrepresents a hydrogen atom or a tri-substituted silyl group, and M represents an alkali metal atom, aluminum, or a magnesium monohalide) and a coordinating additive are caused to act on the acyloxypyranone compound represented by formula (II), to thereby produce an alkyne compound represented by formula (IV). The alkyne compound represented by formula (IV) is hydrolyzed with acid, to thereby produce a dihydrofuran compound represented by formula (V).


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