The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 09, 2014

Filed:

May. 29, 2014
Applicants:

The Broad Institute, Inc., Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Feng Zhang, Cambridge, MA (US);

Le Cong, Cambridge, MA (US);

Patrick Hsu, Cambridge, MA (US);

Fei Ran, Boston, MA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12N 15/00 (2006.01); C07H 21/00 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01);
Abstract

The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for selecting specific cells by introducing precise mutations utilizing the CRISPR-Cas system.

Published as:
CA2894701A1; WO2014093712A1; WO2014093712A9; US2014242664A1; EP2771468A1; US2014273232A1; US8906616B2; EP2771468B1; ES2536353T3; DK2771468T3; PT2771468E; ES2542015T3; AU2013359123A1; PL2771468T3; US2015232882A1; PT2784162E; US2015247150A1; KR20150105633A; HK1202586A1; CN105121648A; ES2553782T3; PT2896697E; JP2016504026A; HK1209153A1; HK1209154A1; HK1210221A1; JP2016093196A; AU2013359123B2; JP2016129516A; JP2016165307A; PT2921557T; AU2016244241A1; US2016340662A1; HK1216759A1; MX2015007549A; ES2598115T3; PL2921557T3; JP6203879B2; JP2017205127A; JP2018099131A; JP6420273B2; RU2015128098A; RU2015128098A3; JP6495395B2; AU2016244241B2; JP2019103510A; JP2019103511A; RU2019127300A; RU2701850C2; AU2019229420A1; JP6726225B2; AU2016244241C1; CN105121648B; CN113528577A; JP6960950B2; JP6960951B2; JP2022023118A; AU2019229420B2; AU2022203762A1; JP7198328B2; JP2023040015A; EP4279588A2; IL307735A; EP4279588A3; IL239344B1; IL239344B2; JP7542595B2; CN113528577B; JP2024170440A; AU2022203762B2; MX380562B; CN119752887A; EP4545636A2; AU2025203780A1; EP4545636A3; US2025250553A1;

Find Patent Forward Citations

Loading…