The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 2014
Filed:
Jun. 19, 2006
Paul Ponath, San Francisco, CA (US);
Patricia Rao, Acton, MA (US);
Michael Rosenzweig, Boston, MA (US);
L. Mary Smith, Hillsborough, NC (US);
Jose F. Ponte, Quincy, MA (US);
Paul Ponath, San Francisco, CA (US);
Patricia Rao, Acton, MA (US);
Michael Rosenzweig, Boston, MA (US);
L. Mary Smith, Hillsborough, NC (US);
Jose F. Ponte, Quincy, MA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention provides binding molecules that specifically bind to ILT3, e.g., human ILT3 (hILT3), on antigen presenting cells, such as for example, monocytes, macrophages and dendritic cells (DC), e.g., monocyte-derived dendritic cells (MDDC). Various aspects of the invention relate to binding molecules, and pharmaceutical compositions thereof. Methods of using the binding molecules of the invention to detect human ILT3 or to modulate human ILT3 activity, either in vitro or in vivo, are also encompassed by the invention.