The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2014

Filed:

Nov. 10, 2011
Applicants:

Ian M. Bell, Harleysville, PA (US);

Mark E. Fraley, North Wales, PA (US);

Steven N. Gallicchio, Horsham, PA (US);

Anthony Ginnetti, Perkasie, PA (US);

Helen J. Mitchell, Richboro, PA (US);

Daniel V. Paone, West Point, PA (US);

Donnette D. Staas, Holland, PA (US);

Cheng Wang, Fort Washington, PA (US);

Blair C. Zartman, Hatfield, PA (US);

Heather E. Stevenson, Ardmore, PA (US);

Inventors:

Ian M. Bell, Harleysville, PA (US);

Mark E. Fraley, North Wales, PA (US);

Steven N. Gallicchio, Horsham, PA (US);

Anthony Ginnetti, Perkasie, PA (US);

Helen J. Mitchell, Richboro, PA (US);

Daniel V. Paone, West Point, PA (US);

Donnette D. Staas, Holland, PA (US);

Cheng Wang, Fort Washington, PA (US);

Blair C. Zartman, Hatfield, PA (US);

Heather E. Stevenson, Ardmore, PA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/90 (2006.01); A61K 31/519 (2006.01); A01N 43/42 (2006.01); A61K 31/44 (2006.01); C07D 487/00 (2006.01); C07D 471/02 (2006.01); C07D 491/02 (2006.01); C07D 498/02 (2006.01); C07D 513/02 (2006.01); C07D 515/02 (2006.01); A61K 31/506 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/506 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention is directed to piperidinone carboxamide indane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.


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