The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2014
Filed:
May. 13, 2009
Masatoshi Narahara, Hitachinaka, JP;
Toshiro Saito, Hitachinaka, JP;
Naoshi Itabashi, Kokubunji, JP;
Jiro Yamamoto, Kokubunji, JP;
Hiroyuki Uchiyama, Kokubunji, JP;
Masatoshi Narahara, Hitachinaka, JP;
Toshiro Saito, Hitachinaka, JP;
Naoshi Itabashi, Kokubunji, JP;
Jiro Yamamoto, Kokubunji, JP;
Hiroyuki Uchiyama, Kokubunji, JP;
Hitachi High-Technologies Corporation, Tokyo, JP;
Abstract
An object of the present invention relates to distinguishing, from a fluorophore of an unreacted substrate, a single fluorophore attached to a nucleotide that is incorporated into a probe by a nucleic acid synthesis. The present invention relates to a nucleic acid analyzing device that analyzes a nucleic acid in sample by fluorescence, wherein a localized surface plasmon is generated by illumination, and a probe for analyzing the nucleic acid in the sample is on the site where the surface plasmon is generated. According to the present invention, since it is possible to efficiently produce fluorescence intensifying effects due to the surface plasmon and to immobilize the probe to a region within the reach of the fluorescence intensifying effects, it becomes possible to measure a nucleic acid synthesis without removing unreacted nucleotide to which fluorophores are attached.