The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2014

Filed:

Mar. 03, 2008
Applicants:

Adrian P. Rowley, Los Angeles, CA (US);

Lucien D. Laude, Rabastens-de-Bigorre, FR;

Mark S. Humayun, Glendale, CA (US);

James D. Weiland, Valencia, CA (US);

Atoosa Lotfi, Valencia, CA (US);

Francis S. Markland, Jr., Manhattan Beach, CA (US);

Inventors:

Adrian P. Rowley, Los Angeles, CA (US);

Lucien D. Laude, Rabastens-de-Bigorre, FR;

Mark S. Humayun, Glendale, CA (US);

James D. Weiland, Valencia, CA (US);

Atoosa Lotfi, Valencia, CA (US);

Francis S. Markland, Jr., Manhattan Beach, CA (US);

Assignee:

Doheny Eye Institute, Los Angeles, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/02 (2006.01); A61L 27/34 (2006.01); A61L 27/50 (2006.01); A61N 1/05 (2006.01); A61N 1/36 (2006.01); A61F 2/14 (2006.01);
U.S. Cl.
CPC ...
A61N 1/0543 (2013.01); A61N 1/36046 (2013.01); A61L 27/34 (2013.01); A61L 2400/18 (2013.01); A61F 2/14 (2013.01); A61L 27/50 (2013.01);
Abstract

The invention provides a biocompatible silicone implant that can be securely affixed to living tissue through interaction with integral membrane proteins (integrins). A silicone article containing a laser-activated surface is utilized to make the implant. One example is an implantable prosthesis to treat blindness caused by outer retinal degenerative diseases. The device bypasses damaged photoreceptors and electrically stimulates the undamaged neurons of the retina. Electrical stimulation is achieved using a silicone microelectrode array (MEA). A safe, protein adhesive is used in attaching the MEA to the retinal surface and assist in alleviating focal pressure effects. Methods of making and attaching such implants are also provided.


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